Tito of Macho Nacho Productions on YouTube is one of the reasons I fell in love with modding Game Boy Advances (Game Boys Advance?) earlier this year and I've been learning more about how to make my retro video games last longer since discs and disc drives are liable to fail at some point.
This particular video on using a Raspberry Pi for loading games is fun, but the buried lede here is that it uses Open PS2 Loader (OPL) to load disk ISOs over a samba/SMB share folder. This is such an awesome feature of OPL for people like me, who host a NAS at home, because it means loading a ton of games is easy and disc free.
What Happens When You Connect A PS2 To A Raspberry Pi? | PSX-Pi SMB Share
Macho Nacho Productions (Youtube)